HISTORY OF SEDATIVE DRUGS – THEIR EVOLUTION IN MEDICINE

two. Histamine Receptor Antagonism: Some sedatives, such as antihistamines, exert their sedative effects by blocking histamine receptors inside the Mind, specifically H1 receptors. Histamine performs a job in wakefulness and arousal, so blocking its effects encourages sedation and sleepiness.Medical doctors and veterinarians normally administer sed